Interference in ACTH immunoassay negatively impacts the management of subclinical hypercortisolism
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DOI: 10.1007/s12020-017-1268-7
Abstract: PurposeLow plasma corticotropin is considered a useful parameter for the diagnosis of subclinical hypercortisolism in patients with an adrenal incidentaloma. However, immunoassays are vulnerable to interference from endogenous antibodies. In this study, subjects who underwent… read more here.
Keywords: corticotropin; interference; one patient; management ... See more keywords
Alteration in skeletal muscle mass in women with subclinical hypercortisolism
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DOI: 10.1007/s12020-018-1598-0
Abstract: PurposeDespite the well-known deleterious effects of cortisol on skeletal muscle, whether subtle cortisol excess in subclinical hypercortisolism (SH) affects skeletal muscle mass is unknown. Our objective was to understand the effects of the cortisol level… read more here.
Keywords: muscle mass; skeletal muscle; muscle; subclinical hypercortisolism ... See more keywords
Do the diagnostic criteria for subclinical hypercortisolism exist?
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DOI: 10.1016/j.ando.2018.03.013
Abstract: "Subclinical hypercortisolism" (SH) refers to a condition associated with a mild chronic increase in cortisol secretion. By definition, patients with SH do not exhibit specific symptoms of overt Cushing's syndrome (such as purple striae, easy… read more here.
Keywords: hypercortisolism exist; criteria subclinical; hypercortisolism; cushing syndrome ... See more keywords
Association Between Aldosterone and Hypertension Among Patients With Overt and Subclinical Hypercortisolism
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DOI: 10.1210/jendso/bvac167
Abstract: Abstract Introduction Hypertension is one of the most common clinical features of patients with overt and subclinical hypercortisolism. Although previous studies have shown the coexistence of autonomous cortisol and aldosterone secretion, it is unclear whether… read more here.
Keywords: hypercortisolism; hypertension; hypertension among; patients overt ... See more keywords
SUN-144 High Prevalence of Diabetes in Patients with Primary Aldosteronism (PA) Associated with Subclinical Hypercortisolism and Prediabetes More Prevalent in Bilateral Than Unilateral PA
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DOI: 10.1210/js.2019-sun-144
Abstract: Abstract INTRODUCTION: Primary aldosteronism (PA) is characterized by the autonomous production of aldosterone, usually from an aldosterone producing adenoma in one adrenal gland or idiopathic hyperaldosteronism, with bilateral adrenal lesions. It has been suggested that… read more here.
Keywords: prevalence diabetes; high prevalence; bilateral unilateral; prevalence ... See more keywords