Association of Subcutaneous or Intravenous Administration of Casirivimab and Imdevimab Monoclonal Antibodies With Clinical Outcomes in Adults With COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.6920
Abstract: Key Points Question Is subcutaneous treatment with casirivimab and imdevimab associated with improved 28-day clinical outcomes compared with nontreatment, and is it clinically similar to intravenously administered casirivimab and imdevimab for outpatients with COVID-19? Findings… read more here.
Keywords: clinical outcomes; casirivimab; casirivimab imdevimab; hospitalization death ... See more keywords
Subcutaneous vs Intravenous Administration of Medications and Fluids for Patients With Cancer in the US and Canada.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2023.0239
Abstract: This cross-sectional study compares rates of subcutaneous and intravenous administration of medications and fluids among patients with cancer in 2 acute palliative care units in the US and Canada. read more here.
Keywords: patients cancer; medications fluids; intravenous administration; administration medications ... See more keywords
Subcutaneous and intravenous belimumab in the treatment of systemic lupus erythematosus: a review of data on subcutaneous and intravenous administration
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2017.1371592
Abstract: ABSTRACT Introduction: Loss of B cell tolerance is a hallmark feature of the pathogenesis of Systemic Lupus Erythematosus (SLE). Recent advances in B cell therapy have focused on targeted therapy aimed at inhibiting B cell… read more here.
Keywords: subcutaneous intravenous; intravenous belimumab; systemic lupus; treatment ... See more keywords
Rapid Switch from Subcutaneous to Intravenous Treprostinil in Precapillary Pulmonary Hypertension by Pump Implantation.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000933
Abstract: Limited data is available on the transition from subcutaneous to intravenous prostacyclin in precapillary pulmonary hypertension. We performed a retrospective analysis of all patients who were switched from subcutaneous to intravenous treprostinil with an implantable… read more here.
Keywords: treprostinil; intravenous treprostinil; subcutaneous intravenous; implantation ... See more keywords
Pharmacokinetics of Trastuzumab After Subcutaneous and Intravenous Administration in Obese Patients
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DOI: 10.1177/1060028020902318
Abstract: Background: Subcutaneous trastuzumab (T-SC) administration does not allow the historical target concentration of 20 µg/mL for efficacy to be reached, from the start of treatment in patients with a body mass index (BMI) >30 kg/m2.… read more here.
Keywords: subcutaneous intravenous; administration; trastuzumab subcutaneous; obese patients ... See more keywords
Pharmacokinetic and pharmacodynamic modelling after subcutaneous, intravenous and buccal administration of a high-concentration formulation of buprenorphine in conscious cats
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0176443
Abstract: Background The aim of this study was to describe the joint pharmacokinetic-pharmacodynamic model and evaluate thermal antinociception of a high-concentration formulation of buprenorphine (Simbadol™) in cats. Methods Six healthy cats (4.9 ± 0.7 kg) were… read more here.
Keywords: subcutaneous intravenous; administration; high concentration; concentration formulation ... See more keywords
Costs of subcutaneous and intravenous administration of trastuzumab for patients with HER2-positive breast cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of comparative effectiveness research"
DOI: 10.2217/cer-2017-0048
Abstract: AIM Trastuzumab is available in an intravenous (iv.) and a subcutaneous (sc.) formulation. The objective of this study was to estimate the costs of administration of iv. and sc. trastuzumab treatment. MATERIALS & METHODS Via… read more here.
Keywords: subcutaneous intravenous; administration; time; administration trastuzumab ... See more keywords
Efficacy and safety of subcutaneous and intravenous rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone in first-line diffuse large B-cell lymphoma: the randomized MabEase study
Sign Up to like & getrecommendations! Published in 2017 at "Haematologica"
DOI: 10.3324/haematol.2017.173583
Abstract: Intravenous rituximab plus chemotherapy is standard treatment for diffuse large B-cell lymphoma. A subcutaneous formulation of rituximab is expected to simplify and shorten drug preparation and administration, and to reduce treatment burden. MabEase (clinicaltrials.gov Identifier:… read more here.
Keywords: rituximab; satisfaction; subcutaneous intravenous; treatment ... See more keywords