A scalable device-less biomaterial approach for subcutaneous islet transplantation.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120499
Abstract: The subcutaneous space has been shown to be a suitable site for islet transplantation, however an abundance of islets is required to achieve normoglycemia, often requiring multiple donors. The loss of islets is due to… read more here.
Keywords: islet; scalable device; islet transplantation; subcutaneous space ... See more keywords
Delivery of Pancreatic Islets and Single Dose Local Immune Suppression Into Subcutaneous Space Using Injectable Hydrogel Provides Indefinite Survival of the Graft in Mouse Model of Diabetes
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DOI: 10.1097/01.tp.0000542657.23034.87
Abstract: Introduction Pancreatic islet transplantation is a promising technique to treat type 1 diabetes. Long-term survival of the graft is required for a successful islet transplantation. Repeated use of immunosuppressive drugs after organ/cell transplantation often leads… read more here.
Keywords: immune; graft; transplantation; subcutaneous space ... See more keywords