IL-20 subfamily cytokines impair the oesophageal epithelial barrier by diminishing filaggrin in eosinophilic oesophagitis
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DOI: 10.1136/gutjnl-2022-327166
Abstract: Objective Disruption of the epithelial barrier plays an essential role in developing eosinophilic oesophagitis (EoE), a disease defined by type 2 helper T cell (Th2)-mediated food-associated and aeroallergen-associated chronic inflammation. Although an increased expression of… read more here.
Keywords: eoe; eosinophilic oesophagitis; epithelial barrier; barrier ... See more keywords