Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2
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DOI: 10.1186/s13073-020-00802-w
Abstract: Background SARS-CoV-2, a positive-sense RNA virus in the family Coronaviridae , has caused a worldwide pandemic of coronavirus disease 2019 or COVID-19. Coronaviruses generate a tiered series of subgenomic RNAs (sgRNAs) through a process involving… read more here.
Keywords: sgrnas; non canonical; viral isolates; subgenomic rnas ... See more keywords
sgDI-tector: defective interfering viral genome bioinformatics for detection of coronavirus subgenomic RNAs
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DOI: 10.1261/rna.078969.121
Abstract: Coronavirus RNA-dependent RNA polymerases produce subgenomic RNAs (sgRNAs) that encode viral structural and accessory proteins. User-friendly bioinformatic tools to detect and quantify sgRNA production are urgently needed to study the growing number of next-generation sequencing… read more here.
Keywords: defective interfering; subgenomic rnas; detection; interfering viral ... See more keywords
Subgenomic RNAs and Their Encoded Proteins Contribute to the Rapid Duplication of SARS-CoV-2 and COVID-19 Progression
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DOI: 10.3390/biom12111680
Abstract: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently widespread throughout the world, accompanied by a rising number of people infected and breakthrough infection of variants, which make the… read more here.
Keywords: replication; encoded proteins; rnas encoded; duplication ... See more keywords
Molecular Characteristics of Subgenomic RNAs and the Cap-Dependent Translational Advantage Relative to Corresponding Genomic RNAs of Tomato spotted wilt virus
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DOI: 10.3390/ijms232315074
Abstract: Tomato spotted wilt virus (TSWV) causes severe viral diseases on many economically important plants of Solanaceae. During the infection process of TSWV, a series of 3′-truncated subgenomic RNAs (sgRNAs) relative to corresponding genomic RNAs were… read more here.
Keywords: genomic rnas; tomato spotted; wilt virus; subgenomic rnas ... See more keywords