Evaluation of Evidence of Statistical Support and Corroboration of Subgroup Claims in Randomized Clinical Trials
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Internal Medicine"
DOI: 10.1001/jamainternmed.2016.9125
Abstract: Importance Many published randomized clinical trials (RCTs) make claims for subgroup differences. Objective To evaluate how often subgroup claims reported in the abstracts of RCTs are actually supported by statistical evidence (P read more here.
Keywords: subgroup findings; subgroup; statistical support; subgroup claims ... See more keywords
Reporting and interpretation of subgroup analyses in heart failure randomized controlled trials
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13122
Abstract: This study aimed to investigate the reporting of subgroup analyses in heart failure (HF) randomized controlled trials (RCTs) and to determine the strength and credibility of subgroup claims. read more here.
Keywords: subgroup; subgroup analyses; analyses heart; heart failure ... See more keywords
PSC subtyping based on TTF‐1 and p40 expression reveals distinct molecular characteristics and therapeutic strategies
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34137
Abstract: Pulmonary sarcomatoid carcinoma (PSC) is a unique form of poorly differentiated nonsmall cell lung cancer (NSCLC) and is notorious for its highly malignant nature and dismal prognosis. To introduce effective treatment for PSC patients, precise… read more here.
Keywords: positive subgroup; distinct molecular; subgroup; three subgroups ... See more keywords
The effects of 45S5 bioactive glass and Er:YAG Laser on the microtensile bond strength of fluorosed teeth
Sign Up to like & getrecommendations! Published in 2020 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.23550
Abstract: This vitro study aimed to evaluate the effects of 45S5 bioactive glass (BAG) and Er:YAG laser as desensitization treatments on the microtensile bond strength (MTBS) of fluorosed teeth. The 120 noncarious fluorosis were to obtain… read more here.
Keywords: bag; fluorosed teeth; subgroup; yag laser ... See more keywords
Consistency‐Based Approach to Adjust for Multiplicity in Confirmatory Subgroup Analysis
Sign Up to like & getrecommendations! Published in 2025 at "Statistics in Medicine"
DOI: 10.1002/sim.70154
Abstract: With the advance of medical sciences and better understanding of human biological systems, the next generation of treatment has shifted toward personalized medicine. It is expected that personalized medicine, such as molecularly targeted anti‐cancer agents,… read more here.
Keywords: treatment; based approach; consistency based; medicine ... See more keywords
Propensity score weighting for causal subgroup analysis
Sign Up to like & getrecommendations! Published in 2021 at "Statistics in Medicine"
DOI: 10.1002/sim.9029
Abstract: A common goal in comparative effectiveness research is to estimate treatment effects on prespecified subpopulations of patients. Though widely used in medical research, causal inference methods for such subgroup analysis (SGA) remain underdeveloped, particularly in… read more here.
Keywords: subgroup; causal; score weighting; subgroup analysis ... See more keywords
Multiply robust subgroup analysis based on a single-index threshold linear marginal model for longitudinal data with dropouts.
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in medicine"
DOI: 10.1002/sim.9386
Abstract: Identifying subpopulations that may be sensitive to the specific treatment is an important step toward precision medicine. On the other hand, longitudinal data with dropouts is common in medical research, and subgroup analysis for this… read more here.
Keywords: data dropouts; medicine; treatment; model ... See more keywords
Large characteristic subgroups with modular subgroup lattice
Sign Up to like & getrecommendations! Published in 2018 at "Archiv der Mathematik"
DOI: 10.1007/s00013-018-1190-0
Abstract: It is known that if a group contains an abelian subgroup of finite index, then it also has an abelian characteristic subgroup of finite index. The aim of this paper is to prove that corresponding… read more here.
Keywords: subgroup; modular subgroup; large characteristic; subgroup lattice ... See more keywords
Evaluating the impact of digital therapy for male LUTS: insights from the BEST trial subgroup analysis
Sign Up to like & getrecommendations! Published in 2025 at "World Journal of Urology"
DOI: 10.1007/s00345-025-06016-2
Abstract: Men with lower urinary tract symptoms (LUTS) represent a heterogeneous patient population. The BEST trial investigated the effectiveness of a digital health application for male LUTS. This pre-specified subgroup analysis evaluated treatment effects based on… read more here.
Keywords: best trial; male luts; subgroup analysis; trial ... See more keywords
Global epigenetic profiling identifies methylation subgroups associated with recurrence-free survival in meningioma
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropathologica"
DOI: 10.1007/s00401-017-1678-x
Abstract: Meningioma is the most common primary brain tumor and carries a substantial risk of local recurrence. Methylation profiles of meningioma and their clinical implications are not well understood. We hypothesized that aggressive meningiomas have unique… read more here.
Keywords: subgroup; methylation; recurrence; recurrence free ... See more keywords
Impact of endometrial carcinoma histotype on the prognostic value of the TCGA molecular subgroups
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05542-1
Abstract: Background The Cancer Genome Atlas (TCGA) identified four prognostic subgroups of endometrial carcinoma: copy-number-low/p53-wild-type (p53wt), POLE-mutated/ultramutated (POLEmt), microsatellite-instability/hypermutated (MSI), and copy-number-high/p53-mutated (p53mt). However, it is still unclear if they may be integrated with the current… read more here.
Keywords: subgroup; carcinoma; non endometrioid; histotype ... See more keywords