Prespecification of subgroup analyses and examination of treatment-subgroup interactions in cancer individual participant data meta-analyses are suboptimal.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of clinical epidemiology"
DOI: 10.1016/j.jclinepi.2021.06.019
Abstract: OBJECTIVES This study aimed to explore the prespecification and conduct of subgroup analyses in cancer individual participant data meta-analyses (IPDMAs). STUDY DESIGN AND SETTING We searched PubMed, Embase, Cochrane Library, and Web of Science to… read more here.
Keywords: subgroup; treatment subgroup; subgroup analyses; cancer ... See more keywords
Using Model-Based Recursive Partitioning for Treatment-Subgroup Interactions Detection in Real-World Data: A Myocardial Infarction Case Study
Sign Up to like & getrecommendations! Published in 2018 at "Studies in health technology and informatics"
DOI: 10.3233/978-1-61499-852-5-576
Abstract: The effects of treatment often vary over subpopulations characterized by baseline patient features. Detection of such treatment-subgroup interaction is of central importance to precision medicine and personalized care. In this paper, we propose an analytical… read more here.
Keywords: medicine; real world; treatment subgroup; treatment ... See more keywords