Articles with "subgroups phase" as a keyword



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Bridging across patient subgroups in phase I oncology trials that incorporate animal data

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Published in 2021 at "Statistical Methods in Medical Research"

DOI: 10.1177/0962280220986580

Abstract: In this paper, we develop a general Bayesian hierarchical model for bridging across patient subgroups in phase I oncology trials, for which preliminary information about the dose–toxicity relationship can be drawn from animal studies. Parameters… read more here.

Keywords: patient subgroups; phase oncology; bridging across; across patient ... See more keywords