Articles with "subinhibitory concentrations" as a keyword



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Mechanisms of biofilm stimulation by subinhibitory concentrations of antimicrobials.

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Published in 2018 at "Current opinion in microbiology"

DOI: 10.1016/j.mib.2018.07.006

Abstract: Biofilms are a typical mode of growth for most microorganisms and provide them with a variety of survival benefits. Biofilms can pose medical and industrial challenges due to their increased tolerance of antimicrobials and disinfectants.… read more here.

Keywords: biofilm stimulation; subinhibitory concentrations; mechanisms biofilm; stimulation subinhibitory ... See more keywords

Effect of subinhibitory concentrations of imipenem and piperacillin on Pseudomonas aeruginosa toxA and exoS transcriptional expression

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Published in 2019 at "New Microbes and New Infections"

DOI: 10.1016/j.nmni.2019.100608

Abstract: Subinhibitory concentrations (subMIC) of antibiotics, although not able to kill bacteria, can modify their physicochemical characteristics and may interfere with some bacterial functions. This study aimed to investigate the effect of subMIC of imipenem and… read more here.

Keywords: subinhibitory concentrations; imipenem piperacillin; expression; concentrations imipenem ... See more keywords

Principles of bacteriostatic and bactericidal antibiotics at subinhibitory concentrations

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Published in 2025 at "mBio"

DOI: 10.1128/mbio.02066-25

Abstract: ABSTRACT Subinhibitory antibiotic exposures are common in clinical and environmental contexts, yet their effects on bacterial growth dynamics remain incompletely understood. We studied the temporal response of Escherichia coli to a panel of bactericidal (“cidal”)… read more here.

Keywords: physiology; subinhibitory concentrations; bacteriostatic bactericidal; growth ... See more keywords

Indole May Help the Horizontal Transmission of Antibiotic Resistance Genes in E. coli Under Subinhibitory Concentrations of Cefotaxime Stress

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Published in 2024 at "Cellular Microbiology"

DOI: 10.1155/2024/9018205

Abstract: Objectives: Subinhibitory concentration of antibiotics in the environment is an important risk factor for the horizontal transmission of antibiotic resistance genes (ARGs). The signaling mechanism of resistance gene transmission remains unknown. The aim of this… read more here.

Keywords: resistance; horizontal transmission; subinhibitory concentrations; indole ... See more keywords

The issue beyond resistance: Methicillin-resistant Staphylococcus epidermidis biofilm formation is induced by subinhibitory concentrations of cloxacillin, cefazolin, and clindamycin

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Published in 2022 at "PLOS ONE"

DOI: 10.1371/journal.pone.0277287

Abstract: Staphylococcus epidermis is one of the most frequent causes of device-associated infections due to biofilm formation. Current reports noted that subinhibitory concentrations of antibiotics induce biofilm production in some bacteria. Accordingly, we evaluated the effect… read more here.

Keywords: clindamycin; biofilm formation; cefazolin clindamycin; cloxacillin cefazolin ... See more keywords

Impact of Subinhibitory Concentrations of Metronidazole on Morphology, Motility, Biofilm Formation and Colonization of Clostridioides difficile

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Published in 2022 at "Antibiotics"

DOI: 10.3390/antibiotics11050624

Abstract: Clostridioides difficile infection (CDI) is the primary cause of health-care-associated infectious diarrhea. Treatment requires mostly specific antibiotics such as metronidazole (MTZ), vancomycin or fidaxomicin. However, approximately 20% of treated patients experience recurrences. Treatment with MTZ… read more here.

Keywords: colonization; clostridioides difficile; morphology; impact subinhibitory ... See more keywords

Nisin Mutant Prevention Concentration and the Role of Subinhibitory Concentrations on Resistance Development by Diabetic Foot Staphylococci

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Published in 2022 at "Antibiotics"

DOI: 10.3390/antibiotics11070972

Abstract: The most prevalent microorganism in diabetic foot infections (DFI) is Staphylococcus aureus, an important multidrug-resistant pathogen. The antimicrobial peptide nisin is a promising compound for DFI treatment, being effective against S. aureus. However, to avoid… read more here.

Keywords: nisin; diabetic foot; resistance; aureus ... See more keywords

Ethanol at Subinhibitory Concentrations Enhances Biofilm Formation in Salmonella Enteritidis

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Published in 2022 at "Foods"

DOI: 10.3390/foods11152237

Abstract: The survival of Salmonella Enteritidis in the food chain is relevant to its biofilm formation capacity, which is influenced by suboptimal environmental conditions. Here, biofilm formation pattern of this bacterium was assessed in the presence… read more here.

Keywords: salmonella enteritidis; ethanol subinhibitory; biofilm formation; subinhibitory concentrations ... See more keywords

The SOS Response Activation and the Risk of Antibiotic Resistance Enhancement in Proteus spp. Strains Exposed to Subinhibitory Concentrations of Ciprofloxacin

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Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms26010119

Abstract: The widespread and inappropriate use of antibiotics, for therapeutic and prophylactic purposes, has contributed to a global crisis of rapidly increasing antimicrobial resistance of microorganisms. This resistance is often associated with elevated mutagenesis induced by… read more here.

Keywords: resistance; sos response; subinhibitory concentrations; proteus ... See more keywords