Population Pharmacokinetic Analysis of Fevipiprant in Healthy Subjects and Asthma Patients using a Tukey’s g-and-h Distribution
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DOI: 10.1055/a-1381-6579
Abstract: The objective of this analysis was to characterize the population pharmacokinetics (PK) of fevipiprant in asthma patients and to evaluate the effect of baseline covariates on the PK of fevipiprant. PK data from 1281 healthy… read more here.
Keywords: asthma patients; analysis; healthy subjects; subjects asthma ... See more keywords
Early onset of airway derecruitment assessed using the forced oscillation technique in subjects with asthma.
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DOI: 10.1152/japplphysiol.00534.2018
Abstract: Derecruitment of air spaces in the lung occurs when airways close during exhalation and is related to ventilation heterogeneity and symptoms in asthma. The forced oscillation technique has been used to identify surrogate measures of… read more here.
Keywords: oscillation technique; volume; subjects asthma; derecruitment ... See more keywords
Use of Systemic Corticosteroids for Reasons Other than Asthma in Subjects with Asthma
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DOI: 10.1159/000518461
Abstract: Backgrounds: Recent studies have reported increased risks of adverse events from systemic corticosteroids even with only low-dose or short-term use. Some patients with asthma experience complications requiring systemic corticosteroids. However, few studies have examined issues… read more here.
Keywords: corticosteroids reasons; reasons asthma; use; systemic corticosteroid ... See more keywords
Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction
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DOI: 10.1172/jci95693
Abstract: BACKGROUND. The link between mucus plugs and airflow obstruction has not been established in chronic severe asthma, and the role of eosinophils and their products in mucus plug formation is unknown. METHODS. In clinical studies,… read more here.
Keywords: airflow obstruction; mucus plugs; mucus plug; mucus ... See more keywords
Trends and factors associated with influenza vaccination in subjects with asthma: analysis of the Korea National Health and Nutrition Examination Survey between 2010 and 2019
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DOI: 10.1177/20406223221123979
Abstract: Background: Despite the importance of influenza vaccination, its rates in subjects with asthma are suboptimal, especially in the young population. Methods: Among 72,843 adults aged ⩾18 years from the Korea National Health and Nutrition Examination Survey… read more here.
Keywords: vaccination rates; vaccination; influenza vaccination; associated influenza ... See more keywords