Evaluation of controlled IL-12 as monotherapy in subjects with recurrent GBM.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.2053
Abstract: 2053 Background: Interleukin-12 (IL-12), a master regulator of the immune system, results in anti-tumor responses in preclinical models, but safe use requires tightly controlled production. It was conditionally produced in Ph1 “main” study (NCT02026271) in… read more here.
Keywords: controlled monotherapy; subjects recurrent; main study; evaluation controlled ... See more keywords
Survival of subjects with recurrent glioblastoma receiving intratumoral administration of controlled IL-12 with limited exposure to dexamethasone.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.2564
Abstract: 2564Background: Interleukin-12 (IL-12) results in anti-tumor responses in preclinical models but requires tightly controlled production to achieve safety and elicit immune system activation to real... read more here.
Keywords: survival subjects; glioblastoma receiving; receiving intratumoral; subjects recurrent ... See more keywords
Immediate changes in trunk muscle activation patterns during a lifting task following an abdominal drawing-in exercise in subjects with recurrent low back pain.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of back and musculoskeletal rehabilitation"
DOI: 10.3233/bmr-191549
Abstract: BACKGROUND The abdominal drawing-in exercise could help improve delayed transversus abdominis (TrA) activation during limb movement in subjects with recurrent low back pain (rLBP). However, little is known about whether the same effect is observed… read more here.
Keywords: activation; muscle; subjects recurrent; abdominal drawing ... See more keywords