A Randomized Thorough QT Study of Apomorphine Sublingual Film in Patients With Parkinson's Disease
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DOI: 10.1002/cpdd.1147
Abstract: A randomized thorough QT study was conducted to assess the effects of apomorphine sublingual film (SL‐APO) on corrected QT interval (QTc) and other cardiac conduction parameters in patients with Parkinson's disease (PD) and “OFF” episodes.… read more here.
Keywords: sublingual film; patients parkinson; parkinson disease; thorough study ... See more keywords
Preparation and evaluation of sublingual film of ketorolac tromethamine
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DOI: 10.1080/03639045.2022.2123925
Abstract: Abstract Objective This research aimed to formulate fast-dissolving sublingual films of Ketorolac tromethamine to improve therapeutic efficacy, patient compliance and overcome the drug’s gastrointestinal side effects by avoiding direct contact with the gastric mucosa. Methods… read more here.
Keywords: sublingual film; dissolution; ratio; film ... See more keywords
Development and Optimization of Asenapine Sublingual Film Using QbD Approach.
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DOI: 10.1208/s12249-021-02132-5
Abstract: Asenapine, an atypical antipsychotic agent, has been approved for the acute and maintenance treatment of schizophrenia and manic episodes of bipolar disorder. However, the extensive hepatic metabolism limits its oral bioavailability. Therefore, the objective of… read more here.
Keywords: asenapine sublingual; optimization asenapine; sublingual film; film using ... See more keywords
FABRICATION OF MICROEMULSION LOADED SUBLINGUAL FILM FOR RAPID ABSORPTION OF FENTANYL CITRATE IN TRANSIENT BREAKTHROUGH PAIN
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DOI: 10.22159/ijap.2021v13i3.40744
Abstract: Objective: The present research work aims to develop a microemulsion loaded sublingual film for rapid absorption of fentanyl citrate in transient breakthrough pain. Methods: The Fentanyl citrate microemulsion loaded sublingual film was prepared using Capmul… read more here.
Keywords: microemulsion; fentanyl citrate; film; sublingual film ... See more keywords