Improvement of Resveratrol Permeation through Sublingual Mucosa: Chemical Permeation Enhancers versus Spray Drying Technique to Obtain Fast-Disintegrating Sublingual Mini-Tablets
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DOI: 10.3390/pharmaceutics13091370
Abstract: Resveratrol (RSV) is a natural polyphenol with several interesting broad-spectrum pharmacological properties. However, it is characterized by poor oral bioavailability, extensive first-pass effect metabolism and low stability. Indeed, RSV could benefit from the advantage of… read more here.
Keywords: permeation enhancers; sublingual mucosa; fast disintegrating; mini tablets ... See more keywords
Development of a Mucoadhesive Vehicle Based on Lyophilized Liposomes for Drug Delivery through the Sublingual Mucosa
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DOI: 10.3390/pharmaceutics14071497
Abstract: A pharmaceutical vehicle based on lyophilized liposomes is proposed for the buccal administration of drugs aimed at systemic delivery through the sublingual mucosa. Liposomes made of egg phosphatidylcholine and cholesterol (7/3 molar ratio) were prepared… read more here.
Keywords: vehicle; sublingual mucosa; lyophilized liposomes; delivery sublingual ... See more keywords