Mucus concentration-dependent biophysical abnormalities unify submucosal gland and superficial airway dysfunction in cystic fibrosis.
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DOI: 10.1126/sciadv.abm9718
Abstract: Cystic fibrosis (CF) is characterized by abnormal transepithelial ion transport. However, a description of CF lung disease pathophysiology unifying superficial epithelial and submucosal gland (SMG) dysfunctions has remained elusive. We hypothesized that biophysical abnormalities associated… read more here.
Keywords: submucosal gland; biophysical abnormalities; airway; mucus ... See more keywords