Extensive subpial cortical demyelination is specific to multiple sclerosis
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DOI: 10.1111/bpa.12813
Abstract: Cortical demyelinated lesions are frequent and widespread in chronic multiple sclerosis (MS) patients, and may contribute to disease progression. Inflammation and related oxidative stress have been proposed as central mediators of cortical damage, yet meningeal… read more here.
Keywords: demyelination; cortical demyelination; extensive subpial; demyelination specific ... See more keywords
Accumulation of meningeal lymphocytes correlates with white matter lesion activity in progressive multiple sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.151683
Abstract: Subpial cortical demyelination is an important component of multiple sclerosis (MS) pathology contributing to disease progression, yet mechanism(s) underlying its development remain unclear. Compartmentalized inflammation involving the meninges may drive this type of injury. Given… read more here.
Keywords: white matter; lesion; activity; subpial cortical ... See more keywords