Single‐Cell and Spatial Transcriptomics Decodes Wharton's Jelly‐Derived Mesenchymal Stem Cells Heterogeneity and a Subpopulation with Wound Repair Signatures
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202204786
Abstract: The highly heterogeneous characteristics of Wharton's jelly mesenchymal stem cells (WJ‐MSCs) may be responsible for the poor clinical outcomes and poor reproducibility of treatments based on WJ‐MSCs. Exploration of WJ‐MSC heterogeneity with multimodal single‐cell technologies… read more here.
Keywords: subpopulation; cell; heterogeneity; single cell ... See more keywords
Transient astrocyte‐like NG2 glia subpopulation emerges solely following permanent brain ischemia
Sign Up to like & getrecommendations! Published in 2021 at "Glia"
DOI: 10.1002/glia.24064
Abstract: NG2 glia display wide proliferation and differentiation potential under physiological and pathological conditions. Here, we examined these two features following different types of brain disorders such as focal cerebral ischemia (FCI), cortical stab wound (SW),… read more here.
Keywords: astrocyte like; like ng2; ng2 glia; subpopulation ... See more keywords
Causal Inference Over a Subpopulation: The Effect of Malaria Vaccine in Women During Pregnancy
Sign Up to like & getrecommendations! Published in 2024 at "Statistics in Medicine"
DOI: 10.1002/sim.10228
Abstract: Preventing malaria during pregnancy is of critical importance, yet there are no approved malaria vaccines for pregnant women due to lack of efficacy results within this population. Conducting a randomized trial in pregnant women throughout… read more here.
Keywords: effect; vaccine; causal inference; pregnancy ... See more keywords
Identification of a Subpopulation of Astrocyte Progenitor Cells in the Neonatal Subventricular Zone: Evidence that Migration is Regulated by Glutamate Signaling
Sign Up to like & getrecommendations! Published in 2025 at "Neurochemical Research"
DOI: 10.1007/s11064-024-04326-2
Abstract: In mice engineered to express enhanced green fluorescent protein (eGFP) under the control of the entire glutamate transporter 1 (GLT1) gene, eGFP is found in all ‘adult’ cortical astrocytes. However, when 8.3 kilobases of the… read more here.
Keywords: migration; tdt; tdt cells; subpopulation ... See more keywords
Immature CD8 Single-Positive Thymocytes Are a Molecularly Distinct Subpopulation, Selectively Dependent on BRD4 for Their Differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.06.007
Abstract: SUMMARY T cell differentiation in the thymus proceeds in an ordered sequence of developmental events characterized by variable expression of CD4 and CD8 coreceptors. Here, we report that immature single-positive (ISP) thymocytes are molecularly distinct… read more here.
Keywords: thymocytes molecularly; subpopulation; differentiation; single positive ... See more keywords
Evolutionary dynamics and the evolution of multiplayer cooperation in a subdivided population.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2017.06.034
Abstract: The classical models of evolution have been developed to incorporate structured populations using evolutionary graph theory and, more recently, a new framework has been developed to allow for more flexible population structures which potentially change… read more here.
Keywords: temperature; evolution; subpopulation; population ... See more keywords
Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular cell"
DOI: 10.1016/j.molcel.2019.02.037
Abstract: Antibiotics can induce mutations that cause antibiotic resistance. Yet, despite their importance, mechanisms of antibiotic-promoted mutagenesis remain elusive. We report that the fluoroquinolone antibiotic ciprofloxacin (cipro) induces mutations by triggering transient differentiation of a mutant-generating… read more here.
Keywords: response; subpopulation; cell subpopulation; reactive oxygen ... See more keywords
Differential Coding of Itch and Pain by a Subpopulation of Primary Afferent Neurons
Sign Up to like & getrecommendations! Published in 2020 at "Neuron"
DOI: 10.1016/j.neuron.2020.03.021
Abstract: Itch and pain are distinct unpleasant sensations that can be triggered from the same receptive fields in the skin, raising the question of how pruriception and nociception are coded and discriminated. Here, we tested the… read more here.
Keywords: itch; differential coding; subpopulation; itch pain ... See more keywords
Critically Endangered subpopulation of Irrawaddy dolphin in central Philippines may lose its habitat to large-scale development project
Sign Up to like & getrecommendations! Published in 2020 at "Oryx"
DOI: 10.1017/s003060532000085x
Abstract: The Irrawaddy dolphin Orcaella brevirostris is a rangerestricted, facultative freshwater species that inhabits coastal, estuarine and freshwater habitats in disjunct populations from India to South-east Asia. The Iloilo-Guimaras Straits subpopulation is one of three known… read more here.
Keywords: irrawaddy dolphin; development; irrawaddy; subpopulation ... See more keywords
A high-frequency phenotypic switch links bacterial virulence and environmental survival in Acinetobacter baumannii
Sign Up to like & getrecommendations! Published in 2018 at "Nature microbiology"
DOI: 10.1038/s41564-018-0151-5
Abstract: Antibiotic-resistant infections lead to 700,000 deaths per year worldwide1. The roles of phenotypically diverse subpopulations of clonal bacteria in the progression of diseases are unclear. We found that the increasingly pathogenic and antibiotic-resistant pathogen Acinetobacter… read more here.
Keywords: phenotypic switch; subpopulation; acinetobacter baumannii; acinetobacter ... See more keywords
Investigating root and canal morphology of anterior and premolar teeth using CBCT with a novel coding classification system in Saudi subpopulation
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-86277-4
Abstract: Understanding root canal morphology is essential for successful endodontic treatment. This study aimed to investigate morphological variations in root and canal systems of anterior and premolar teeth across different age groups and genders in a… read more here.
Keywords: age; system; anterior premolar; premolar teeth ... See more keywords