Determining subpopulation methylation profiles from bisulfite sequencing data of heterogeneous samples using DXM
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DOI: 10.1093/nar/gkab516
Abstract: Abstract Epigenetic changes, such as aberrant DNA methylation, contribute to cancer clonal expansion and disease progression. However, identifying subpopulation-level changes in a heterogeneous sample remains challenging. Thus, we have developed a computational approach, DXM, to… read more here.
Keywords: methylation; sequencing data; bisulfite sequencing; methylation profiles ... See more keywords