Variant WWTR1 gene fusions in epithelioid hemangioendothelioma—A genetic subset associated with cardiac involvement
Sign Up to like & getrecommendations! Published in 2020 at "Genes"
DOI: 10.1002/gcc.22839
Abstract: The genetic hallmark of epithelioid hemangioendothelioma (EHE) is a recurrent WWTR1‐CAMTA1 fusion, which is present in most cases bearing a conventional histology. A subset of cases is characterized by a distinct morphology and harbors instead… read more here.
Keywords: wwtr1 maml2; wwtr1 gene; wwtr1; epithelioid hemangioendothelioma ... See more keywords
Integrated epigenomic and transcriptomic analysis reveals TP63 as a novel player in clinically aggressive chronic lymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.31999
Abstract: Chronic lymphocytic leukemia (CLL) stereotyped subsets #6 and #8 include cases expressing unmutated B cell receptor immunoglobulin (BcR IG) (U‐CLL). Subset #6 (IGHV1‐69/IGKV3‐20) is less aggressive compared to subset #8 (IGHV4‐39/IGKV1(D)‐39) which has the highest… read more here.
Keywords: cll; lymphocytic leukemia; chronic lymphocytic; subset ... See more keywords
Clinical value of negative 68Ga-PSMA PET/CT in the management of biochemical recurrent prostate cancer patients
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-04914-8
Abstract: Purpose To evaluate the clinical value of 68 Ga-PSMA PET/CT negativity in patients with biochemical recurrent prostate cancer (BCR). Methods One hundred three BCR patients (median age, 70 years; median PSA, 0.47 ng/mL) with negative 68 Ga-PSMA… read more here.
Keywords: subset; prostate cancer; subset subset; psma pet ... See more keywords
Hierarchical cluster analysis of cytokine profiles reveals a cutaneous vasculitis-associated subgroup in dermatomyositis
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05339-2
Abstract: Dermatomyositis (DM) is a chronic inflammatory autoimmune disease with notable heterogeneity. The intent of this study was to explore the difference in cytokine profiles of different subsets in DM based on the disease activity and… read more here.
Keywords: vasculitis; cytokine; cluster analysis; subset ... See more keywords
Zero-dimensional CDH spaces with a dense completely metrizable subset
Sign Up to like & getrecommendations! Published in 2019 at "Acta Mathematica Hungarica"
DOI: 10.1007/s10474-019-00989-4
Abstract: Given a separable metrizable h-homogeneous space X, it is proved that X is a \(\textsf{CDH}\) space with a dense completely metrizable subspace if and only if every countable subset of X is included in a… read more here.
Keywords: dimensional cdh; completely metrizable; zero dimensional; dense completely ... See more keywords
Fixed points of locally nonexpansive mappings in geodesic spaces
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Mathematical Analysis and Applications"
DOI: 10.1016/j.jmaa.2016.09.059
Abstract: This is an examination of the structure of fixed point sets of locally nonexpansive mappings in various geodesic spaces. Among other things, it is shown that if G is a bounded connected open subset of… read more here.
Keywords: fixed points; points locally; nonexpansive mappings; subset ... See more keywords
Definition of a mouse microglial subset that regulates neuronal development and proinflammatory responses in the brain
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2116241119
Abstract: Significance CD11c+ microglia enriched for osteopontin (OPN) expression appear at distinct stages of brain development, aging, and several neurodegenerative disorders. Whether coexpression of CD11c and OPN results from microglial activation or represents a part of… read more here.
Keywords: cd11c; definition; microglial subset; development ... See more keywords
Definition of the contribution of an Osteopontin-producing CD11c+ microglial subset to Alzheimer's disease.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2218915120
Abstract: Alzheimer's disease (AD) is the most common form of incurable dementia and represents a critical public health issue as the world's population ages. Although microglial dysregulation is a cardinal feature of AD, the extensive heterogeneity… read more here.
Keywords: microglial subset; disease; alzheimer disease; producing cd11c ... See more keywords
Peripheral blood lymphocyte subset repertoires are biased and reflect clinical features in patients with dermatomyositis
Sign Up to like & getrecommendations! Published in 2019 at "Scandinavian Journal of Rheumatology"
DOI: 10.1080/03009742.2018.1530371
Abstract: Objective: Dermatomyositis (DM) is an idiopathic inflammatory myopathy which often involves the lungs. DM is likely to be associated with aberrant T- and B-cell activation in the pathogenesis because of the proven effectiveness of T-… read more here.
Keywords: blood lymphocyte; clinical features; lymphocyte subset; subset repertoires ... See more keywords
Increased Peripheral NKG2A-NKG2D+CD3-CD16+CD56dim NK Cell Subset Was Positively Correlated with Antiphospholipid Antibodies in Patients of Obstetric Antiphospholipid Syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "Immunological investigations"
DOI: 10.1080/08820139.2020.1835949
Abstract: Obstetric antiphospholipid syndrome (OAPS) is an autoimmune disorder with severe life-threatening complications shown during pregnancy. It has been reported that the increase in CD16+CD56dim natural killer (NK) cells in peripheral blood are risk factors for… read more here.
Keywords: nkg2a nkg2d; cd16; cd16 cd56dim; subset ... See more keywords
Successful deployment of drug-disease interaction clinical decision support across multiple Kaiser Permanente regions
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American Medical Informatics Association : JAMIA"
DOI: 10.1093/jamia/ocz020
Abstract: OBJECTIVE The study sought to develop a criteria-based scoring tool for assessing drug-disease knowledge base content and creation of a subset and to implement the subset across multiple Kaiser Permanente (KP) regions. MATERIALS AND METHODS… read more here.
Keywords: across multiple; disease; multiple kaiser; drug disease ... See more keywords