Amyloid precursor protein products concentrate in a subset of exosomes specifically endocytosed by neurons
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DOI: 10.1007/s00018-017-2664-0
Abstract: Amyloid beta peptide (Aβ), the main component of senile plaques of Alzheimer’s disease brains, is produced by sequential cleavage of amyloid precursor protein (APP) and of its C-terminal fragments (CTFs). An unanswered question is how… read more here.
Keywords: subset exosomes; precursor protein; app; amyloid precursor ... See more keywords