WIN site inhibition disrupts a subset of WDR5 function
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DOI: 10.1038/s41598-022-05947-9
Abstract: WDR5 nucleates the assembly of histone-modifying complexes and acts outside this context in a range of chromatin-centric processes. WDR5 is also a prominent target for pharmacological inhibition in cancer. Small-molecule degraders of WDR5 have been… read more here.
Keywords: site inhibition; subset wdr5; win site; site ... See more keywords