Kinetic resolution via supramolecular iminium catalysis: multiactivation enables the asymmetric synthesis of β-aryl substituted aldehydes and densely functionalized cyclohexanes.
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DOI: 10.1039/c7cc01625e
Abstract: The kinetic resolution of β-aryl substituted 1,7-dioxo compounds with α,β-unsaturated aldehydes affording enantioenriched β-aryl substituted aldehydes as well as densely functionalized cyclohexanes is presented. The two enantioenriched products were obtained in reasonable yields with high… read more here.
Keywords: aryl substituted; functionalized cyclohexanes; kinetic resolution; densely functionalized ... See more keywords
Direct conversion of γ,γ-dicarbonyl-substituted aldehydes into γ-lactones with a sodium chlorite/DBDMH combination
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DOI: 10.1039/c7gc00144d
Abstract: An unprecedented and challenging simultaneous carboxylation/halogenation, and next lactonization of γ,γ-dicarbonyl-substituted aldehydes has been realized using an eco-friendly, safe and inexpensive solid sodium chlorite (NaClO2)/1,3-dibromo-5,5-dimethyl-hydantoin (DBDMH) combination. This new reaction is amenable to a multi-gram… read more here.
Keywords: dicarbonyl substituted; dbdmh combination; substituted aldehydes; sodium chlorite ... See more keywords