Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2019.1634064
Abstract: Abstract 17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1) is a key enzyme in the biosynthesis of 17β-estradiol. Novel estrone-based compounds bearing various 15β-oxa-linked substituents and hydroxy, methoxy, benzyloxy, and sulfamate groups in position C3 as potential 17β-HSD1… read more here.
Keywords: cofactor dependent; hsd1; substituted alkoxy; synthesis substituted ... See more keywords
Synthesis and Fungicidal Activity of Substituted N-(Alkoxy)-1-(3-pyridinyl)methanonimines
Sign Up to like & getrecommendations! Published in 2019 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363219110045
Abstract: A number of new substituted N-(alkoxy)-1-phenyl- and N-(alkoxy)-1-cyclohexyl-1-(3-pyridinyl)-methanonymines were prepared by reacting the corresponding N-hydroxyl derivatives with benzyl chloride under phase transfer catalysis in a 10% NaOH-benzene system, as well as with 1-bromohexane and bromocyclohexane… read more here.
Keywords: fungicidal activity; synthesis fungicidal; pyridinyl; substituted alkoxy ... See more keywords