Pd-catalyzed enantioselective cyclopropanation of nitriles with mono substituted allyl carbonates enabled by the bulky N-heterocyclic carbene ligand.
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DOI: 10.1039/c9cc01960j
Abstract: A highly efficient catalyst for Pd-catalyzed cyclopropanation was developed using a bulkier N-heterocyclic carbene ligand, with which the nitriles reacted with mono substituted allyl reagents to afford cyclopropanes in high yields with high cyclopropanation/allylation and… read more here.
Keywords: cyclopropanation; mono substituted; carbene ligand; substituted allyl ... See more keywords