Regio- and Enantioselective Iridium-Catalyzed Amination of Alkyl-Substituted Allylic Acetates with Secondary Amines.
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DOI: 10.1021/acs.orglett.1c04135
Abstract: Robust air-stable cyclometalated π-allyliridium C,O-benzoates modified by (S)-tol-BINAP catalyze the reaction of secondary aliphatic amines with racemic alkyl-substituted allylic acetates to furnish products of allylic amination with high levels of enantioselectivity. Complete branched regioselectivities were… read more here.
Keywords: amination; regio enantioselective; substituted allylic; alkyl substituted ... See more keywords