Synthesis, antimalarial activity, heme binding and docking studies of N-substituted 4-aminoquinoline-pyrimidine molecular hybrids.
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DOI: 10.1016/j.ejmech.2017.02.024
Abstract: A series of novel N-substituted 4-aminoquinoline-pyrimidine hybrids have been synthesized via simple and economic route and evaluated for their antimalarial activity. Most compounds showed potent antimalarial activity against both CQ-sensitive and CQ-resistant strains with high… read more here.
Keywords: substituted aminoquinoline; aminoquinoline pyrimidine; antimalarial activity; activity ... See more keywords