Synthesis and Analgesic Activity of 4,7-Dimethyl-3,4,4a,5,8,8a-Hexahydro-2-Chromen-4,8-Diols Containing Alkyl-Substituted Aromatic Moieties
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DOI: 10.1007/s10600-017-2202-1
Abstract: A series of new heterocyclic compounds with the hexahydro-2H-chromene skeleton were prepared by reacting the monoterpenoid para-mentha-1,8-diene-5,6-diol with 4-alkyl-substituted aromatic aldehydes. Adding small alkyl substituents (methyl and ethyl) to the aldehyde aromatic ring increased the… read more here.
Keywords: activity dimethyl; alkyl substituted; substituted aromatic; synthesis analgesic ... See more keywords
Untargeted DNA Adductomics Identifies Aristolochic Acid III as a Potent DNA-Damaging Agent among 11 Substituted Aromatic Genotoxicants in the Rat Urinary System.
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DOI: 10.1021/acs.chemrestox.5c00126
Abstract: An untargeted, data-independent acquisition high-resolution accurate tandem mass spectrometry method using an Orbitrap mass spectrometer was employed to screen for DNA adducts formed from 11 environmental and dietary aromatic or substituted aromatic carcinogens in the… read more here.
Keywords: urinary system; substituted aromatic; amino; acid iii ... See more keywords
A promising catalyst for exclusive para hydroxylation of substituted aromatic hydrocarbons under UV light
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DOI: 10.1039/c7gc01653k
Abstract: Herein, we describe a waterborne polymer/carbon dot nanocomposite system as an efficient, resourceful and sustainable photocatalyst for para-selective hydroxylation of substituted aromatic compounds using H2O2 under UV light. The polymer matrix and carbon dot generate… read more here.
Keywords: para hydroxylation; hydroxylation; substituted aromatic; hydroxylation substituted ... See more keywords
Electroenzymatic Cascade Synthesis of Chiral α-Substituted Aromatic Halohydrins from Alkene: A Green and Stereoselective Approach
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DOI: 10.1039/d5gc04446d
Abstract: Chiral α-substituted aromatic halohydrins are vital intermediates in pharmaceutical development and asymmetric synthesis. Herein, we report a sustainable electroenzymatic cascade for their synthesis directly from alkene. This one-pot strategy integrates... read more here.
Keywords: electroenzymatic cascade; chiral substituted; aromatic halohydrins; cascade synthesis ... See more keywords
Discovery of Novel Potential Aphid Repellents: Geranic Acid Esters Containing Substituted Aromatic Rings
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DOI: 10.3390/molecules27185949
Abstract: Aphids are one of the most damaging agricultural pests. For the sake of novel eco-friendly compounds with good activity for aphid control, a series of novel geranic acid esters containing substituted aromatic rings were designed… read more here.
Keywords: substituted aromatic; acid esters; activity; esters containing ... See more keywords