New 2-(2-pyridyl)-substituted benzothiazoles with polyethylene glycol substituents
Sign Up to like & getrecommendations! Published in 2019 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-019-2468-5
Abstract: An approach for the synthesis of new organic ligands combining in their structure pyridine, benzothiazole, and polyethylene glycol fragments was developed, proceeding from 6-hydroxy-2-(pyridin-2-yl)benzothiazole and mono- or ditosyl-substituted polyethylene glycols. The ligand 2-(2-{[2-(pyridin-2-yl)benzothiazol-6-yl]oxy}ethoxy)ethanol (L) in… read more here.
Keywords: substituted benzothiazoles; h2o; new pyridyl; pyridyl substituted ... See more keywords
Fast and high-efficiency synthesis of 2-substituted benzothiazoles via combining enzyme catalysis and photoredox catalysis in one-pot.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104607
Abstract: An efficient and green method, combining enzymatic and visible-light catalysis for synthesis of the widely applicable 2-substituted benzothiazoles, has been developed. This method features a relay catalysis protocol consisting of biocatalytic promiscuity and visible-light-induced subsequent… read more here.
Keywords: high efficiency; substituted benzothiazoles; visible light; catalysis ... See more keywords
Peroxide-mediated oxidative coupling of primary alcohols and disulfides: Synthesis of 2-substituted benzothiazoles
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.05.021
Abstract: Abstract A peroxide-mediated protocol for the synthesis of 2-substituted benzothiazoles was developed, starting from bis( o -aminophenyl) disulfides and primary alcohols. Eleven differently 2-substituted benzothiazoles were prepared in moderate to excellent yields using di- tert… read more here.
Keywords: synthesis substituted; primary alcohols; substituted benzothiazoles; mediated oxidative ... See more keywords
Synthesis, Antiproliferative Evaluation and QSAR Analysis of Novel Halogen- and Amidino-Substituted Benzothiazoles and Benzimidazoles
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232415843
Abstract: Syntheses of 6-halogen-substituted benzothiazoles were performed by condensation of 4-hydroxybenzaldehydes and 2-aminotiophenoles and subsequent O-alkylation with appropriate halides, whereas 6-amidino-substituted benzothiazoles were synthesized by condensation of 5-amidino-2-aminothiophenoles and corresponding benzaldehydes. While most of the compounds… read more here.
Keywords: halogen; cell; substituted benzothiazoles; amidino ... See more keywords
Synthetic Approaches to Biologically Active C-2-Substituted Benzothiazoles
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27082598
Abstract: Numerous benzothiazole derivatives are used in organic synthesis, in various industrial and consumer products, and in drugs, with a wide spectrum of biological activity. As the properties of the benzothiazole moiety are strongly affected by… read more here.
Keywords: substituted benzothiazoles; synthetic approaches; chemistry; active substituted ... See more keywords