Hetaryl-substituted bicyclo[1.1.1]pentanes (microreview)
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02558-7
Abstract: Synthesis and properties of heterocycles bearing bicyclo[1.1.1]pentane moiety attached to the heterocyclic ring are summarized in this microreview. In particular, heterocyclizations with bicyclo-[1.1.1]pentane derivatives, as well as reactions involving incorporation of the preexisting heterocyclic system… read more here.
Keywords: bicyclo pentanes; bicyclo pentane; hetaryl substituted; substituted bicyclo ... See more keywords
Synthesis of Sulfur-Substituted Bicyclo[1.1.1]pentanes by Iodo-Sulfenylation of [1.1.1]Propellane
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DOI: 10.1021/acs.orglett.2c02875
Abstract: Thiols easily react with [1.1.1]propellane to give sulfur-substituted bicyclo[1.1.1]pentanes in radical reactions, but this reactivity is not replicated in the case of heterocyclic thiols. Herein, we address this issue by electrophilically activating [1.1.1]propellane to promote… read more here.
Keywords: bicyclo pentanes; iodo sulfenylation; sulfur substituted; substituted bicyclo ... See more keywords
Selective [2σ + 2σ] Cycloaddition Enabled by Boronyl Radical Catalysis: Synthesis of Highly Substituted Bicyclo[3.1.1]heptanes.
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DOI: 10.1021/jacs.2c13740
Abstract: In contrast to the traditional and widely-used cycloaddition reactions involving at least a π bond component, a [2σ + 2σ] radical cycloaddition between bicyclo[1.1.0]butanes (BCBs) and cyclopropyl ketones has been developed to provide a modular,… read more here.
Keywords: selective cycloaddition; cycloaddition; enabled boronyl; substituted bicyclo ... See more keywords