The potential of employing substituted bis[3-hydroxy-2-(pyrimidin-2-yl)-2Н-pyrazol-4-yl]methane for the synthesis of symmetrical N,O-macroheterocycles with a dioxacycloalkane central fragment
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-019-02409-5
Abstract: O-cyclialkylation of substituted bis[3-hydroxy-2-(pyrimidin-2-yl)-2H-pyrazol-4-yl]methane by α,ω-dibromoalkanes with a hydrocarbon chain length of up to three CH2 groups has been carried out. A novel pyrazolophane, 1,6-dioxacycloundecane with symmetrically annulated fragments of 1-(pyrimidin-2-yl)-1H-pyrazole, was isolated and characterized… read more here.
Keywords: pyrazol; pyrimidin pyrazol; substituted bis; hydroxy pyrimidin ... See more keywords
A sustainable strategy for the synthesis of bis-2-iminothiazolidin-4-ones utilizing novel series of asymmetrically substituted bis-thioureas as viable precursors
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DOI: 10.1039/c8ra01253a
Abstract: A novel series of asymmetrically substituted bis-thioureas has been synthesized in an effective pattern via the reaction of diamines with isothiocyanates utilizing the ultrasonic irradiation as a sustainable energy source. This reaction performs well at… read more here.
Keywords: series asymmetrically; novel series; bis thioureas; substituted bis ... See more keywords
Antiparallel Arrangement of 2,7-Substituted 9,10-Bis(phenylethynyl)anthracene Assisted by Hydrogen Bonding of Terminal Units
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DOI: 10.1246/bcsj.20190156
Abstract: 2,7-Substituted 9,10-bis(phenylethynyl)anthracenes with bulky phenol residues were synthesized and investigated for their antiparallel molecular arrangement. UV-vis absorption and photoluminescence... read more here.
Keywords: antiparallel arrangement; arrangement substituted; substituted bis; bis phenylethynyl ... See more keywords
Synthesis and Biological Evaluation of Heterocyclic Substituted Bis(indolyl)methanes.
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DOI: 10.2174/1570179417666200124103400
Abstract: Bis(indolyl)methane derivatives, also considering as metabolites of indole alkaloids, are widely found in nature with a broad range of biological and pharmacological activities. In this work, a series of heterocyclic substituted bis(indolyl)methanes (3a-3p) have been… read more here.
Keywords: indolyl methanes; bis indolyl; substituted bis; heterocyclic substituted ... See more keywords
Synthesis and optical properties of new 5'-aryl-substituted 2,5-bis(3-decyl-2,2'-bithiophen-5-yl)-1,3,4-oxadiazoles
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DOI: 10.3762/bjoc.13.34
Abstract: New photoluminescent donor–acceptor–donor (DAD) molecules, namely 5'-aryl-substituted 2,5-bis(3-decyl-2,2'-bithiophen-5-yl)-1,3,4-oxadiazoles were prepared by palladium-catalyzed coupling from readily available compounds such as ethyl 3-decyl-2,2'-bithiophene-5-carboxylate and aryl halides. The obtained compounds feature increasing bathochromic shifts in their emission spectra… read more here.
Keywords: aryl substituted; substituted bis; bithiophen oxadiazoles; decyl bithiophen ... See more keywords
Novel Set of Highly Substituted Bis-pyridines: Synthesis, Molecular Docking and Drug-Resistant Antibacterial Profile.
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DOI: 10.4155/fmc-2022-0196
Abstract: Aims: Development of antimicrobial agents having the ability to prevent bacterial biofilm formation which causes serious health problems, especially with antibiotic-resistant bacterial strains. Materials and methods: The use of 1,3-diaryl enones as structural motifs to… read more here.
Keywords: bis; bis pyridines; substituted bis; drug resistant ... See more keywords