Straightforward access to densely substituted chiral succinimides through enantioselective organocatalyzed Michael addition of α-alkyl-cyclic ketones to maleimides
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DOI: 10.1039/c9qo01463b
Abstract: A simple organocatalytic system provides efficient access to a series of densely substituted chiral succinimides bearing a quaternary–tertiary carbon stereocenter sequence in good yields, with high diastereo- and enantioselectivities through enantioselective conjugate addition of unreactive… read more here.
Keywords: alkyl cyclic; ketones maleimides; substituted chiral; densely substituted ... See more keywords