Synthesis and antibacterial evaluation of 13-substituted cycloberberine derivatives as a novel class of anti-MRSA agents.
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DOI: 10.1016/j.ejmech.2018.08.050
Abstract: A series of new 13-substituted cycloberberine (CBBR) derivatives were prepared and evaluated for their antibacterial activities against Gram-positive bacteria taking CBBR as the lead. Structure-activity relationship revealed that the introduction of a suitable electron-donating group… read more here.
Keywords: substituted cycloberberine; anti mrsa; derivatives novel; mrsa agents ... See more keywords