Synthesis of trifluoromethyl and trifluoroacetyl substituted dihydropyrrolizines and tetrahydroindolizines
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DOI: 10.1016/j.tetlet.2020.151633
Abstract: Abstract The trifluoroacetic anhydride promoted cyclization of enaminones derived from proline or pipecolic acid and β-ethoxyvinyl trifluoromethyl ketone was reinvestigated. An operationally simple procedure for the selective synthesis of bicyclic trifluoromethylated pyrroles and bicyclic pyrroles… read more here.
Keywords: trifluoromethyl trifluoroacetyl; substituted dihydropyrrolizines; trifluoroacetyl substituted; synthesis trifluoromethyl ... See more keywords