Piperazine and piperidine‐substituted 7‐hydroxy coumarins for the development of anti‐inflammatory agents
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DOI: 10.1002/ardp.202000354
Abstract: Coumarins (2H‐1‐benzopyran‐2‐one), derivatives that can be isolated from several plants, have been reported for their anticoagulant, antimicrobial, anti‐inflammatory, or anticancer activity. Some of these structures are currently approved for the treatment of cardiovascular diseases, as… read more here.
Keywords: anti inflammatory; piperazine piperidine; piperidine substituted; hydroxy coumarins ... See more keywords
Synthesis and Physicochemical and Biological Properties of 8-Amino-Substituted 7-(2-Hydroxy-3-p-Methoxyphenoxypropyl-1)Theophyllines
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DOI: 10.1007/s10600-017-2094-0
Abstract: A method was developed to prepare previously unreported 8-amino-substituted (2-hydroxy-3-p-methoxyphenoxypropyl-1)theophyllines as potential biologically active compounds. Their physicochemical properties; acute toxicity; and diuretic, anti-inflammatory, analgesic, and antihypoxic activity were studied. read more here.
Keywords: methoxyphenoxypropyl theophyllines; synthesis physicochemical; hydroxy methoxyphenoxypropyl; amino substituted ... See more keywords