Synthesis of N-substituted imidazo[4,5-e]benzo[1,2-c;3,4-c’]difuroxans
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DOI: 10.1007/s11172-017-1991-5
Abstract: N-Substituted imidazo[4,5-e]benzo[1,2-c;3,4-c’]difuroxans were synthesized by phase-transfer catalyzed alkylation of imidazo[4,5-e]benzo[1,2-c;3,4-c’]difuroxan salts with various alkylating agents. Acid hydrolysis of N-(ethoxycarbonylmethyl)imidazo[4,5-e]benzo-[1,2-c;3,4-c’]difuroxans gives the corresponding carboxylic acids. Structures of the synthesized compounds were confirmed by NMR spectroscopy, high… read more here.
Keywords: benzo difuroxans; benzo; imidazo benzo; synthesis substituted ... See more keywords
Biological Activity of Amidino-Substituted Imidazo [4,5-b]pyridines
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DOI: 10.3390/molecules28010034
Abstract: A series of cyano- and amidino-substituted imidazo[4,5-b]pyridines were synthesized using standard methods of organic synthesis, and their biological activity was evaluated. Biological evaluation included in vitro assessment of antiproliferative effects on a diverse selection of… read more here.
Keywords: imidazo pyridines; amidino; biological activity; activity ... See more keywords