Articles with "substituted imidazopyridine" as a keyword



Design, synthesis and evaluation of 2, 6, 8-substituted Imidazopyridine derivatives as potent PI3Kα inhibitors

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Published in 2023 at "Journal of Enzyme Inhibition and Medicinal Chemistry"

DOI: 10.1080/14756366.2022.2155638

Abstract: Abstract Inhibition of PI3K pathway has become a desirable strategy for cancer treatment. In this work, a series of 2, 6, 8-substituted Imidazo[1,2-a]pyridine derivatives were designed and screened for their activities against PI3Kα and a… read more here.

Keywords: substituted imidazopyridine; design synthesis; derivatives potent; evaluation substituted ... See more keywords