Synthesis of N‐Substituted Iminosugar Derivatives and Evaluation of Their Immunosuppressive Activities
Sign Up to like & getrecommendations! Published in 2018 at "ChemMedChem"
DOI: 10.1002/cmdc.201700706
Abstract: It is important to find more effective and safer immunosuppressants, because clinically used immunosuppressive agents have significant side effects. A series of N‐substituted iminosugar derivatives were designed and synthesized, and their immunosuppressive effects were evaluated… read more here.
Keywords: inhibitory effects; derivatives evaluation; substituted iminosugar; synthesis substituted ... See more keywords
Synthesis of N-Substituted Iminosugar C-Glycosides and Evaluation as Promising α-Glucosidase Inhibitors
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27175517
Abstract: A series of N-substituted iminosugar C-glycosides were synthesized and tested for α-glucosidase inhibition. The results suggested that 6e is a promising and potent α-glucosidase inhibitor. Enzymatic kinetic assays indicated that compound 6e may be classified… read more here.
Keywords: substituted iminosugar; glucosidase; synthesis substituted; iminosugar glycosides ... See more keywords