Rhodium-Catalyzed [4 + 2] Cascade Annulation to Easy Access N-Substituted Indenoisoquinolinones.
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DOI: 10.1021/acs.orglett.3c01032
Abstract: An efficient approach for the synthesis of N-substituted indenoisoquinolinones via rhodium(III)-catalyzed C-H bond activation/subsequent [4 + 2] cyclization starting from easily available 2-phenyloxazolines and 2-diazo-1,3-indandiones has been developed. A series of indeno[1,2-c]isoquinolinones were obtained in… read more here.
Keywords: catalyzed cascade; cascade annulation; annulation; rhodium catalyzed ... See more keywords