Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans
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DOI: 10.3390/molecules27248808
Abstract: The design of enantiopure stereoisomers of N-2-phenylcyclopropylmethyl-substituted ortho-c oxide-bridged phenylmorphans, the E and Z isomers of an N-cinnamyl moiety, and N-propyl enantiomers were based on combining the most potent oxide-bridged phenylmorphan (the ortho-c isomer) with… read more here.
Keywords: enantiopure; bridged phenylmorphans; substituted ortho; oxide bridged ... See more keywords
Efficient synthesis of 4-substituted-ortho-phthalaldehyde analogues: toward the emergence of new building blocks
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DOI: 10.3762/bjoc.15.67
Abstract: 4-Methoxy-ortho-phthalaldehyde and 4-hydroxy-ortho-phthalaldehyde are potentially useful molecules for fluorimetric analysis of a variety of amines and for the elaboration of complex molecular architectures. Nevertheless, literature generally describes their synthesis in very low yield (below 5%),… read more here.
Keywords: substituted ortho; ortho phthalaldehyde; phthalaldehyde; synthesis substituted ... See more keywords