Synthesis, anticancer activity, structure-activity relationship and binding mode of interaction studies of substituted pentanoic acids.
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DOI: 10.4155/fmc-2018-0361
Abstract: Aim: Simultaneous inhibition of MMP-2 and HDAC8 may be an effective strategy to target cancer. Methodology: In continuation of our earlier efforts, a series of substituted pentanoic acids (1-18) were synthesized and checked for their… read more here.
Keywords: synthesis anticancer; anticancer activity; pentanoic acids; activity structure ... See more keywords