Cascade 1,3-dipolar Cycloaddition/SO2 extrusion approach for the rapid synthesis of tetraaryl-substituted pyrazoles with Aggregation Induced Emission characteristics
Sign Up to like & getrecommendations! Published in 2020 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131568
Abstract: Abstract A highly efficient strategy was developed for the straightforward synthesis of tetraaryl-substituted pyrazoles. The cascade process consists of a regioselective 1,3-dipolar cycloaddition of benzosultam-3-ylidenes with nitrile imines and a subsequent elimination of SO2. The… read more here.
Keywords: aggregation induced; substituted pyrazoles; induced emission; tetraaryl substituted ... See more keywords
Arene Binuclear Ru(II)-Promoted Sustainable Synthesis of Substituted Pyrazoles from Alcohols via Acceptorless Dehydrogenative Annulation.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c01452
Abstract: We report a selective and sustainable synthesis of substituted pyrazoles via an eco-friendly acceptorless dehydrogenative annulation (ADA) of greener alcohols, malononitrile, and various aromatic hydrazides by newly synthesized binuclear Ru(II) p-cymene complexes. A discrete set… read more here.
Keywords: dehydrogenative annulation; synthesis substituted; sustainable synthesis; substituted pyrazoles ... See more keywords
Silver-catalyzed decarboxylative cyclization for the synthesis of substituted pyrazoles from 1,2-diaza-1,3-dienes and α-keto acids.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc01793h
Abstract: A silver-catalyzed decarboxylative cyclization process has been developed for the synthesis of substituted pyrazoles from the readily available 1,2-diaza-1,3-dienes and α-keto acids. Under the optimized conditions, a series of multisubstituted pyrazoles were well prepared in… read more here.
Keywords: diaza dienes; synthesis substituted; decarboxylative cyclization; substituted pyrazoles ... See more keywords
Synthesis of Substituted Pyrazoles from Aryl-Sydnones.
Sign Up to like & getrecommendations! Published in 2022 at "Current organic synthesis"
DOI: 10.2174/1570179419666220322121022
Abstract: BACKGROUND In this current work, a new synthesis strategy was developed to obtain 1,3,4-trisubstituted pyrazoles derivatives. METHODS A series of 1,3,4-trisubstituted pyrazoles have been prepared via 1,3-dipolar cycloaddition reaction of 3-phenylsydnones with a variety of… read more here.
Keywords: pyrazoles aryl; synthesis substituted; synthesis; substituted pyrazoles ... See more keywords