Enantioselective Michael addition of 3-ethyl carboxylate substituted pyrazolones to 5-alkenyl thiazolones catalyzed by squaramide organocatalyst
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DOI: 10.1016/j.tetlet.2018.04.083
Abstract: Abstract Asymmetric Michael addition between 3-ethyl carboxylate substituted pyrazolones and 5-alkenylthiazolones catalyzed by a series of chiral bifunctional hydrogen bonding organocatalysts was investigated. Good yields (up to 96%) and excellent enantioselectivities (up to 99% ee)… read more here.
Keywords: carboxylate substituted; addition ethyl; michael addition; substituted pyrazolones ... See more keywords
Asymmetric Chlorination of 4-Substituted Pyrazolones Catalyzed by Chiral Copper Complexes
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DOI: 10.1055/s-0039-1690879
Abstract: A fast and highly enantioselective chlorination of 4-pyrazolones catalyzed by bis(oxazoline)–Cu(ClO4)2·6H2O complexes has been developed. Under the optimized conditions, a series of pyrazolones bearing stereogenic chlorine-attached carbon centers were obtained in moderate to high yields… read more here.
Keywords: chlorination substituted; asymmetric chlorination; chlorination; catalyzed chiral ... See more keywords