Silver‐Catalyzed Synthesis of Substituted Pyridine Derivatives from N‐Propargylic α‐Enamino Esters
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201700559
Abstract: A wide range of substituted pyridine derivatives were synthesized in moderate to good yields from a N-propargylic α-enamino ester. The synthetic strategy involves regioselective addition of propargyl amine to the α-carbon of the alkynyl ester… read more here.
Keywords: substituted pyridine; synthesis; propargylic enamino; pyridine derivatives ... See more keywords
Synthesis, Biological Evaluation, and 3D-QSAR Studies of N-(Substituted pyridine-4-yl)-1-(substituted phenyl)-5-trifluoromethyl-1H-pyrazole-4-carboxamide Derivatives as Potential Succinate Dehydrogenase Inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c05702
Abstract: A series of new fungicides that can inhibit the succinate dehydrogenase (SDH) was classified and named as SDH inhibitors by the Fungicide Resistance Action Committee in 2009. To develop more potential SDH inhibitors, we designed… read more here.
Keywords: carboxamide derivatives; pyrazole carboxamide; trifluoromethyl pyrazole; substituted pyridine ... See more keywords
Metal-Free Synthesis of C-4 Substituted Pyridine Derivatives Using Pyridine-boryl Radicals via a Radical Addition/Coupling Mechanism: A Combined Computational and Experimental Study.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b00823
Abstract: Density functional theory investigations revealed that the pyridine-boryl radical generated in situ using 4-cyanopyridine and bis(pinacolato)diboron could be used as a bifunctional "reagent", which serves as not only a pyridine precursor but also a boryl… read more here.
Keywords: mechanism; addition; pyridine boryl; substituted pyridine ... See more keywords