Articles with "substituted pyrimidine" as a keyword



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Interaction Of 5-Substituted Pyrimidine Nucleoside Analogues And M.Tuberculosis: A View Through An Electron Microscope.

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Published in 2020 at "Biochimie"

DOI: 10.1016/j.biochi.2020.03.004

Abstract: The data of transmission electron microscopy (TEM) on morphology of M. tuberculosis H37Rv bacterial cells treated with four analogues of pyrimidine nucleosides with different substituents at 5 position of base are presented. We showed that… read more here.

Keywords: interaction substituted; substituted pyrimidine; tuberculosis; pyrimidine nucleoside ... See more keywords
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Fused and Substituted Pyrimidine Derivatives as a Profound Anticancer Agent.

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Published in 2020 at "Anti-cancer agents in medicinal chemistry"

DOI: 10.2174/1871520620666200721104431

Abstract: The rationale behind drug design is strategic utilization of heterocyclic fragments with specific physicochemical properties to form molecular targeted agents. Among the heterocyclic molecules, pyrimidine has proved to be a privileged pharmacophore for various biological… read more here.

Keywords: fused substituted; chemistry; substituted pyrimidine; pyrimidine derivatives ... See more keywords