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Published in 2020 at "Biochimie"
DOI: 10.1016/j.biochi.2020.03.004
Abstract: The data of transmission electron microscopy (TEM) on morphology of M. tuberculosis H37Rv bacterial cells treated with four analogues of pyrimidine nucleosides with different substituents at 5 position of base are presented. We showed that…
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Keywords:
interaction substituted;
substituted pyrimidine;
tuberculosis;
pyrimidine nucleoside ... See more keywords
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Published in 2020 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520620666200721104431
Abstract: The rationale behind drug design is strategic utilization of heterocyclic fragments with specific physicochemical properties to form molecular targeted agents. Among the heterocyclic molecules, pyrimidine has proved to be a privileged pharmacophore for various biological…
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Keywords:
fused substituted;
chemistry;
substituted pyrimidine;
pyrimidine derivatives ... See more keywords