Articles with "substituted pyrroloindolines" as a keyword



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Synthesis and Activation of Bench-Stable 3a-Fluoropyrroloindolines as Latent Electrophiles for the Synthesis of C-2-Thiol-Substituted Tryptophans and C-3a-Substituted Pyrroloindolines.

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Published in 2019 at "Organic letters"

DOI: 10.1021/acs.orglett.9b02972

Abstract: Indole dearomatization of tryptophan represents a key approach in the synthesis of indole containing alkaloids. Although the reactivity of C-3a-bromo-, 3a-iodo-, and 3a-chloropyrroloindolines has been explored, the utility and reactivity of C-3a-fluoropyrroloindolines has remained untapped.… read more here.

Keywords: substituted tryptophans; tryptophans substituted; activation bench; thiol substituted ... See more keywords