Novel one pot synthesis of substituted quinazolin-4(3H)-ones and pyrazolo[4,3-d]pyrimidin-7(6H)-ones using copper iodide, azides and terminal alkynes
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DOI: 10.1016/j.tetlet.2017.06.026
Abstract: A simple and highly efficient copper iodide catalyzed one-pot synthesis of 2-substituted quinazolin-4(3H)-ones have been developed from anthranilamide, terminal alkynes and azides. A wide variety of alkynes were screened to understand the scope of this… read more here.
Keywords: substituted quinazolin; pot synthesis; synthesis substituted; copper iodide ... See more keywords
Synthesis and Evaluation of Antioxidant Properties of 2-Substituted Quinazolin-4(3H)-ones
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DOI: 10.3390/molecules26216585
Abstract: Quinazolinones represent an important scaffold in medicinal chemistry with diverse biological activities. Here, two series of 2-substituted quinazolin-4(3H)-ones were synthesized and evaluated for their antioxidant properties using three different methods, namely DPPH, ABTS and TEACCUPRAC,… read more here.
Keywords: substituted quinazolin; antioxidant activity; antioxidant properties; quinazolin ones ... See more keywords