Synthesis of Difluoromethyl-Substituted Quinazolines through Selective Difluoromethylation
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DOI: 10.1055/a-1375-3538
Abstract: A highly selective difluoromethylation of quinazolines has been achieved by using commercially available ethyl bromodifluoroacetate as difluorocarbene precursor, providing the corresponding difluoromethyl substituted quinazoline derivatives with up to 83% yield. read more here.
Keywords: synthesis difluoromethyl; difluoromethyl substituted; substituted quinazolines; selective difluoromethylation ... See more keywords