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Published in 2019 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363219070247
Abstract: A series of thieno-pyrimidine derivatives are synthesized from 5′-amino-2,3′-bithiophene-4′-carboxylate via the corresponding intermediate N-benzoylated carboxamide derivatives. The target compounds are tested for antibacterial and antifungal activity. Some of the synthesized compounds demonstrate potent antibacterial activity…
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Keywords:
thieno pyrimidine;
derivatives antimicrobial;
substituted thieno;
synthesis new ... See more keywords
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Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15070820
Abstract: Malaria remains one of the major health problems worldwide. The increasing resistance of Plasmodium to approved antimalarial drugs requires the development of novel antiplasmodial agents that can effectively prevent and/or treat this disease. Based on…
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Keywords:
substituted thieno;
pyrimidines dual;
thieno pyrimidines;
stage ... See more keywords