Ligand-based pharmacophore model for generation of active Antidepressant-like agents from substituted 1,3,5 triazine class.
Sign Up to like & getrecommendations! Published in 2018 at "Current computer-aided drug design"
DOI: 10.2174/1573409915666181219125415
Abstract: Although the transition of a lead candidate into a drug is currently structured by well-defined milestone, it is still most challenging and offers no guarantee in success to the end. In fact, Ligand-based pharmacophore modeling… read more here.
Keywords: ligand based; based pharmacophore; substituted triazine; pharmacophore model ... See more keywords
Substituted 1,3,5-Triazine Hexacarboxylates as Potential Linkers for MOFs
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24193480
Abstract: Hexacarboxylates are promising linkers for MOFs such as NU-109 or NU-110, which possess large values for surfaces and pore volumina. Starting from 2,4,6-tris(bromoaryl)-1,3,5-triazines, palladium-catalyzed cross coupling reactions (Suzuki-Miyaura, Sonogashira-Hagihara) form elongated hexacarboxylate linkers. Eight new… read more here.
Keywords: triazine hexacarboxylates; substituted triazine; potential linkers; tris ... See more keywords