LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "substituted triazine" as a keyword



Tri‐substituted 1,3,5‐triazine‐based analogs as effective HIV‐1 non‐nucleoside reverse transcriptase inhibitors (NNRTIs): A systematic review

Sign Up to like & get
recommendations! Published in 2024 at "Drug Development Research"

DOI: 10.1002/ddr.22154

Abstract: Non‐nucleoside reverse transcriptase inhibitors (NNRTIs) have significantly impacted the HIV‐1 wild‐type due to their high specificity and superior potency. As well as different combinations of NNRTIs have been used on clinically approved combining highly active… read more here.

Keywords: hiv; non nucleoside; drug; nucleoside reverse ... See more keywords

Novel Thio-Substituted 1,3,5-Triazine Compounds as CX3CR1 Modulators for Treating Cardiovascular Diseases

Sign Up to like & get
recommendations! Published in 2025 at "ACS Medicinal Chemistry Letters"

DOI: 10.1021/acsmedchemlett.5c00678

Abstract: Provided herein are novel thio-substituted 1,3,5-triazine compounds as CX3CR1 modulators, pharmaceutical compositions, use of such compounds in treating cardiovascular diseases, and processes for preparing such compounds. read more here.

Keywords: triazine compounds; thio substituted; cx3cr1 modulators; novel thio ... See more keywords

Ligand-based pharmacophore model for generation of active Antidepressant-like agents from substituted 1,3,5 triazine class.

Sign Up to like & get
recommendations! Published in 2018 at "Current computer-aided drug design"

DOI: 10.2174/1573409915666181219125415

Abstract: Although the transition of a lead candidate into a drug is currently structured by well-defined milestone, it is still most challenging and offers no guarantee in success to the end. In fact, Ligand-based pharmacophore modeling… read more here.

Keywords: ligand based; based pharmacophore; substituted triazine; pharmacophore model ... See more keywords
Photo by sxy_selia from unsplash

Substituted 1,3,5-Triazine Hexacarboxylates as Potential Linkers for MOFs

Sign Up to like & get
recommendations! Published in 2019 at "Molecules"

DOI: 10.3390/molecules24193480

Abstract: Hexacarboxylates are promising linkers for MOFs such as NU-109 or NU-110, which possess large values for surfaces and pore volumina. Starting from 2,4,6-tris(bromoaryl)-1,3,5-triazines, palladium-catalyzed cross coupling reactions (Suzuki-Miyaura, Sonogashira-Hagihara) form elongated hexacarboxylate linkers. Eight new… read more here.

Keywords: triazine hexacarboxylates; substituted triazine; potential linkers; tris ... See more keywords