Synthesis of dithienoquinazolines from pyrimidines via intramolecular nucleophilic aromatic substitution of hydrogen
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DOI: 10.1007/s10593-017-2188-4
Abstract: The possibility of intramolecular nucleophilic aromatic substitution of hydrogen in the series of 5-[2-(het)aryl-1-benzothiophen-3-yl]-pyrimidines was explored. A convenient method for the synthesis of [1]benzothieno-[3,2-f]thieno[2,3-h]quinazoline and [1]benzothieno-[3,2-f]thieno[3,2-h]quinazoline based on the developed SNH protocol was proposed. The… read more here.
Keywords: nucleophilic aromatic; aromatic substitution; intramolecular nucleophilic; substitution hydrogen ... See more keywords