Structure-Guided Engineering Unveils Deeper Substrate Channel in Processive Endoglucanase EG5C-1 Contributing to Enhanced Catalytic Efficiency and Processivity.
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DOI: 10.1021/acssynbio.4c00562
Abstract: Processive endoglucanases have generated significant interest due to their bifunctionality in the degradation of cellulose and low product inhibition. However, enhancing their catalytic efficiency through engineering remains a formidable challenge. To address this bottleneck, our… read more here.
Keywords: substrate channel; catalytic efficiency; eg5c; processive endoglucanase ... See more keywords